Genome Projects

Because of our unique and long-standing expertise in genome annotation, as well as our expertise in documenting ancient whole genome duplication (WGD) events, our lab has been, and still is, involved in many international genome projects.

Methusalem

Early 2021, seven Ghent University research groups received funding so that they can develop projects throughout the next 7 years. Our research group was one of them. The Methusalem program offers the most prestigious and extensive funding from the Ghent University Special Research Fund. A total of 27.5 million euros have been allocated for a period of 7 years.

Experimental Evolution

At present, knowledge about the (eco-)evolutionary effects of polyploidy is largely based on either the comparison of contemporary polyploids with their diploid ancestors' descendants, or based on signatures of Whole Genome Duplications (WGDs) in present-day plant genomes. These comparative methods, although informative, suffer from potential biases introduced by evolution of both the polyploid and the descendants of its ancestors after establishment.

Artificial Evolution

Alongside studying the evolution of duplicated genomes through experimental evolution, we also investigate the evolution of polyploid genomes using computer-based in-silico simulations. These simulations involve tracking the evolution of (duplicated) artificial genomes that encode gene regulatory networks, providing valuable insights into the dynamics and adaptation of polyploid systems.

Seagrass Genomics

Seagrasses are unique flowering plants, adapted to a fully submerged existence in the highly saline environment of the ocean, where they must root in reducing sediments, endure chronic light limitation and withstand considerable hydrodynamic forces. In spite of these obstacles, the 80 or so species are among the most widely distributed flowering plants with recently measured estimates of coverage ranging from 600,000 km² to a modeled value of 1.6 million km².